The nightmare isn't over, General Cain ordered The Hive to be reopened, and in doing so contaminated all of Raccoon City, a city of the dead, with Alice stuck right in the middle. Now, along with other surviors, Jill Valentine, Carlos Oliviera and his Captain, Nicholai, they must fight to survive, to escape the nightmare that has plaqed Raccoon City. But now there is a new threat: Matt Addison has fully mutated into a seemingly unstoppable creature, code named Nemesis, who will stop at nothing until everything around it is dead, but it also has another agenda...
Milla Jovovich ... Alice
Sienna Guillory ... Jill Valentine
Oded Fehr ... Carlos Olivera
Thomas Kretschmann ... Major Cain
Sophie Vavasseur ... Angie Ashford
Razaaq Adoti ... Peyton Wells (as Raz Adoti)
Jared Harris ... Dr. Ashford
Mike Epps ... L.J.
Sandrine Holt ... Terri Morales
Matthew G. Taylor ... Nemesis
Zack Ward ... Nicholai Ginovaeff
Iain Glen ... Dr. Isaacs
Dave Nichols ... Captain Henderson
Stefan Hayes ... Yuri Loginova
Geoffrey Pounsett ... Mackenzie