True Image can't be beat for breadth of features. It runs from within Windows or from a Linux-based boot disc, creates full and incremental images, and also backs up single files and folders. It offers the usual compression and encryption options, and if you opt for the more expensive Workstation version you can also purchase a Universal Restore module that will restore images to a PC with a different hardware profile from the one that the image was created on.
Version 11's interface is friendlier, though still unintuitive at times, and there are some very useful new features; Try & Decide mode works like a proactive Windows Restore, writing changes to the program's Secure Zone hidden recovery partition and only committing them later at your discretion. Turn it on before you install unfamiliar software or browse to suspicious Web sites. In my gold beta there was a noticeable performance hit, but it's a nice safeguard to have.
You can also now restore individual files and folders from a full image within the main program, perform a quick system state backup, and there's improved filtering and masking for file and folder backup. The interface may be befuddling in spots, but True Image is the best all-around backup solution on the market.