In Miami, four small time thieves leaded by Ski decide to rob a bank in the small town of Maysville. The lord Hustle demands a 10% commission and sends his experienced bodyguard Ackson to help the gang in their plan. He goes to the target bank to check the security system, but Ski decides to anticipate the plan for that afternoon. They succeed in the heist, but Deputy Kate activates the alarm and one of the criminals shoots Deputy Duff. When the bank is under siege of the police force, they are attacked by weird creatures. The former government agent Hunter comes to the bank and tells that the vampire zombies had been contaminated by an experimental virus developed by the government through the subjects that have escaped from the laboratory, attacking people in the New Moon to feed themselves. The group joins force to survive to the massive attack of the creatures.