Go to GameCopyWorld, type in Earth 2160 and download the latest region fix.
After downloading drag and drop all files into the game directory. Replace the files.
Download a KeyGen for the game. http://gf.wiretarget.com/kg/gdx-e2kg.zip
Put in the serial and then activate by phone and you will be able to play the game after you put in the Verification code.
If anyone knows an easier method please post in comments section because I pieced this together from various things on the internet. The keygen is in German but you'll be able to figure it out no problem. I didn't create this torrent, just uploading because the seeds are very f-ing low.