Dream.2 Middle Weight Grandprix 2008 1st Round was a mixed martial arts event promoted by Dream. It took place on Tuesday, April 29, 2008 at the Saitama Super Arena in Saitama City, Japan.
The event hosted the opening round of the promotion's Middleweight Grand Prix. All bouts were conducted under Dream Rules, (first round is 10 minutes, second round is 5 minutes) in an 84 kilograms (185 lb) weight class. The evening's Main Event featured Kazushi Sakuraba of Japan and Brazilian kyokushin karateka Andrews Nakahara. It attracted a crowd of 21,397 and was broadcast live across Japan on the SkyPerfect pay-per-view.
The Middleweight champion was determined in Dream 6.