Speed Grapher follows the exploits of former war photographer Tatsumi Saiga, who investigates a secret fetish club for the ultra-wealthy. He tries to photograph the club's "goddess", a 15-year-old girl named Kagura, but is discovered. As he is about to be killed, Kagura kisses him, granting him the ability to destroy anything he photographs. Kagura's body fluids can give people bizarre abilities related to their fetishes or obsessions. The story develops as Saiga aims to grant Kagura's desire (her freedom), while on the run from the Roppongi Club and the Tennouzu Group mega-corporation that operates it.
In later episodes, we learn that Kagura's body fluids contain a chemical that activates the dormant Euphoria virus that is responsible for the transformation of humans into Euphorics, such as Saiga. This virus has the rare ability to attach itself to the victim's DNA and alter their body on a genetic level, granting them supernatural powers. Apparently, to become a Euphoric, the virus must be carried before absorbing Kagura's fluid. Failure to carry the virus beforehand results in death.
Speed Grapher is could also be considered a critique of the capitalism and materialism of modern Japanese society. Kagura is the daughter of the wealthiest woman in the world, but she is kept prisoner and nearly starved. Her mother, Shinsen Tennozou, bribes any person who tries to help Kagura. The main villain, as a display of his own vast wealth and power, smokes cigarettes rolled with 10,000 yen bills. In a stark juxtaposition, the male protagonist of the series is a photographer whose lifestyle and beliefs contrast greatly with those of the antagonists. His self-sacrifice and personal aversion of greed is what ultimately saves him and those around him.
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Speed Grapher is in Dual Audio English/Japanese