Dr. Billy Grant (Lowe) took the gamble of his life when he leaves behind the world of emergency medicine to become the in-house doctor of a high-end Las Vegas casino, where he attends to the round-the-clock medical needs of guests, employees and their families amid the lures of Sin City.
Rob Lowe as Dr. Billy Grant
Joe Pantoliano as Tommy Canterna
Amy Adams as Alice Doherty
Sarah Lancaster as Veronica Harold
Tom Sizemore as Vic Moore