While waiting for his complicated surgery, Toussaint is surprised with a visit from two of his former band mates from "The Saints" – Paul and Rick. The old friends discuss the good times they once shared and Toussaint's love affair with Michelle Owens. Toussaint and band mate Leland once came to blows over Michelle causing Toussaint to leave the group. Leland surprises his old friend and shows up in his hospital room. The visit is anything but friendly as Leland says that there were many times where he wished Toussaint were dead. His wish might now come true.
Under pressure from Mr. Lovell, Jolene sees Toussaint's surgery as an opportunity for her next strike. Jason becomes suspicious of Jolene and has Spinelli start investigating her past and her whereabouts when all of the mishaps started happening at the hospital. Jason later interrupts Jolene's plan to swap medications before Toussaint's surgery.
Patrick and Leyla continue hooking up every chance they get. Although things seem to be going well, Leyla is having second thoughts. Leyla tries to break things off with Patrick knowing that she will lose focus on her nursing goals. Her fears come true when Dr. Ford calls her on a mistake that could have cost the life of a patient.
Cody watches as Mac starts to arrest Lainey for her father's murder. Cody "gets caught" stealing meds and blames Lainey for his actions. He then goes on to say that he killed her father to get back at Lainey for not helping him. Cody later tells Lainey that he wasn't willing to see her get pegged for his actions.
Toussaint's surgery seemingly goes well until a vessel bursts and sends all the doctors in panic mode. As Toussaint starts to flatline, his past memories of "The Saints" blur with current memories as the group sings their biggest hit.
Sneak Peak – Rival gangs bring their turf war to the hospital.