18-year-old George Lass (Ellen Muth) dies when a toilet from the MIR space station falls from the sky and hits her. However, soon she discovers that afterlife really does exist... she becomes a reaper - she helps in catching the souls of people moments before they're destined to die. Then she meets a group of reapers who collect people's souls. The main reaper is Rube (Mandy Patinkin), who is always playing smart, Roxy (Jasmine Guy), a reaper with an attitude, Mason (Callum Blue), a confused and funny reaper and Daisy (Laura Harris), a beautiful reaper full of mysteries. The other characters include George's family - mother Joy (Cynthia Stevenson), father Clancy (Greg Kean) and sister Reggie (Britt McKillip), who each have their own way to deal with George's death.
Now that she has a new life, George will try to deal with her new job as a reaper and the fact that she is dead. While learning some important lessons, George gets a job at Happy Days, a office leaded by Delores Herbig (played by Christine Willes), a funny woman who is always optimistic and tries to be everybody's friend while leading a perfect life. The other recurring characters include Crystal (Crystal Dahl), a Happy Days secretary that does not talk way too much and Der Waffle House's waitress Kiffany (Patricia Idlette).