Chris Parker (Shue) is a high school senior that her date (Whitford) stands her up. The only thing she can do now is babysit Brad (Coogan) and Sara (Brewton) Anderson, and their annoying sex fiend neighbor Darryl (Rapp). When her friend Brenda (Miller) is trapped in a bus station, Chris has to travel out of the suburbs to the big city. While there and with a flat tire, Chris, Brad, Sara, and Darryl get caught in the middle of a mafia deal lead by Dan Lynch (Newbern) because of a Playboy magazine. Will they be able to get back to the 'burbs?