Truth: Red, White & Black, the WWII Super Soldier program of 1942, operated by "Reinstein" (Wilfred Nagel, employing an alias previously used by Dr. Abraham Erskine), used African American test subjects to re-create the formula that turned Steve Rogers into Captain America. The clandestine experimentation that empowered Isaiah held similarities with the Tuskegee Syphilis Study.
Project: Rebirth began as a collaboration between US, British and German eugenicists led by Dr. "Josef Reinstein" (real name Dr. Wilfred Nagel), and Dr. Koch. When WW II began, Koch took over the German program and Josef Reinstein took over the American program. Each was attempting to re-create a super soldier program which had turned Steve Rogers into Captain America a year prior to Pearl Harbor. Reinstein's early attempts to refine the formula resulted in African-American super soldiers. Three hundred of these soldiers were taken from Camp Cathcart and subjected to potentially fatal experiments at an undisclosed location in an attempt to re-create the Super Soldier formula. Only five subjects survived the original trials.
One survivor of the experiments, considered to be the "Black" Captain America, Isaiah Bradley became an underground legend among much of the African-American community in the Marvel Universe. A number of the most noted Africans and African-Americans of the twentieth century's last four decades visited Bradley as a sign of respect and, in many cases, hero worship. His visitors have included Malcolm X, Richard Pryor, Muhammad Ali, Angela Davis, Alex Haley, Nelson Mandela, and Colin Powell. Outside the Black community, however, he remains largely unknown. When he arrived as a special guest to the wedding of Storm and the Black Panther, Luke Cage was awestruck while Wolverine was totally unaware of the man's identity or importance.