George & Kathy Lutz and Kathy's 3 children are moving into an elegant Long Island home. What they don't know is that 6 gruesome murders were committed there the year before - Ronald DeFeo Jr., the oldest son in the family, murdered his parents, his 2 brothers & 2 sisters by shooting them with a .35 caliber in November of 1974. No sooner are the Lutzes moved into the house than they begin seeing horrible things - the ghost of Jodie DeFeo, horribly disfigured bodies - and hearing ghostly voices throughout the house. George seems to notice it the most, and it isn't long before he becomes a danger to those around him. When the local priest, called in to bless the house, comes charging out in horror after being swarmed by flies, he issues a dire warning to Kathy - 'Leave that house'. But will they be able to escape before the house and its vengeful spirits take control of George - and make him into a deadly menace?